Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease ...

A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and necroptosis—early in ischemic stroke recovery, exacerbating brain injury. This discovery ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

Recently discovered genetic mutations, modern diagnostic techniques, and fresh approaches to therapy change the outlook on hemochromatosis. Ben, age 46, visited his primary-care clinician with ...

Study reveals liraglutide's potential to regulate iron metabolism and improve glucose tolerance in a mouse model of hereditary hemochromatosis and obesity. Study: Liraglutide Impacts Iron Homeostasis ...

Osteoporosis is a frequent complication in β-thalassemia patients with iron overload, primarily driven by iron-induced oxidative damage and subsequent bone loss. Strategies that promote iron ...

Myelodysplastic syndromes (MDS) are hematological malignancies characterized by ineffective hematopoiesis and increased apoptosis in the bone marrow, which cause peripheral cytopenia. Mitochondria are ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

Researchers at the University of Toronto and Toronto General Hospital have made a discovery that could prevent damage to the heart, pancreas and pituitary gland from excess iron with a simple pill.

For people who need blood transfusions, iron can accumulate in the heart and liver, causing damage and sometimes death. Doctors often prescribe medications called chelators that bind to iron and ...