Regulation of microtubule dynamics is essential for many cell biological processes and is likely to be variable between different subcellular regions. We describe a computational approach to analyze ...

Cellular life hinges on a network of hollow cables called microtubules dynamically lengthening and shortening according to the needs of the moment. During cell division, for instance, these cables ...

A large number of cellular processes depend on the cytoskeleton, a filamentous scaffold of proteins that pervades the cytoplasm and extends all the way from the plasma membrane to the nucleus. In ...

Prof. Meng Wenxiang's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences recently reported a new mechanism by which microtubule networks instruct ...

In a study recently published in the journal Nano Letters, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kanazawa, Japan, used frequency-modulated atomic force ...

Patients with Parkinson's disease suffer a specific loss of dopaminergic neurons from the midbrain region that controls motor function. The exact mechanism of this selective neurodegeneration is ...

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide. Microtubule fibres ...

A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...

Microtubules help to regulate cell structure throughout our bodies. A group of researchers have used cryo-electron microscopy to shed light on how a certain protein keeps microtubules stable, and ...

The chromosomes, once they have duplicated genetic information, move to the center of the cell and the cell, in a very remarkable way, quickly sprouts from its two ends large tubes that hook the ...

Microtubules, the dynamic filaments that form the cell's internal scaffolding, have long been viewed as mere passive structural supports. But a new study reveals they play a far more active signaling ...

An image of a large segment of a microtubule with a peeling tip. The colors highlight the different protofilaments that make up the tubule. The protofilaments are long biopolymers consisting of the ...